From Abuse to Recovery by Scientific American Editors

Author:Scientific American Editors
Language: eng
Format: epub
Publisher: The Rosen Publishing Group, Inc
Published: 2013-08-08T00:00:00+00:00

Underlying such cognitive and behavioral effects may be subtle structural changes too small to show up on brain scans. In a 1997 study psychologists Terry E. Robinson and Bryan Kolb of the University of Michigan at Ann Arbor found that high injected doses of amphetamine in rats cause the major output neurons of the nucleus accumbens to sprout longer branches, or dendrites, as well as additional spines on those dendrites. A decade later Castner’s team linked lower doses of amphetamine to subtle atrophy of neurons in the prefrontal cortex of monkeys.

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